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The FGloop

The crystal structures of cytochrome P450s solved to date have different length FG loops with differing mobility. In P450-BM3, there is a large open channel to the active site and there is disorder in this loop at the entrance to the channel [3,7].


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Wade et al. (1996) Fundamentals of Enzyme-Ligand Interactions in Cytochrome P450cam
POPE5 Conference Proceedings
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